Manchester United vs Southampton LIVE: Premier League result, final score and reaction

OFF THE LINE! United almost put through their own net! That's the closest either side has come as Wan-Bissaka hacks clear on his own goal line. Walker-Peters charged past Rashford to hit the byline and saw his cross diverted goalwards by McTominay, only for Wan-Bissaka to bail him out!

McTominay and Fernandes are playing in the middle in a 4-4-1 for United now. Sancho has started this half through the middle, with Antony on the right and Rashford to the left.

Casemiro is the first player to receive two red cards in a single Premier League season for Manchester United since Nemanja Vidic in 2013-14. The Red Devils beat Crystal Palace 2-1 when he last received his marching orders last month, but they were already 2-0 up when he saw red on that occasion. This will represent a more difficult challenge.

No further changes for United at the break. Southampton are likely to step things up in the next 45 minutes, but the Red Devils are often at their best with space to run into and will fancy their chances of troubling Saints.

Southampton kick us off for the second half! Can they make their numerical advantage count?

While United have carved out chances through neat interplay from Antony, Rashford and Fernandes, they looked slightly unbalanced from the off, an issue which will only be exacerbated by Casemiro's absence. McTominay has come on to add some steel in midfield, but relegation-threatened Southampton will see this as a great chance to earn three valuable points!

Anthony Taylor blows the half-time whistle, and he is met by a chorus of boos from the United faithful after sending Casemiro off for his challenge on Alcaraz. It's still 0-0 at Old Trafford, but there has been plenty of incident. Rashford and Walcott squandered good chances at either end in a lively opening, with Southampton looking bright even before Casemiro's red card, which was given following a VAR review when he caught Alcaraz with his studs high. An intriguing second half awaits!