Liverpool vs Manchester United LIVE: Premier League result, final score and reaction

The hosts kick us off and we are under way!

The two teams enter the Anfield pitch in front of a predictably red-hot atmosphere. We are moments away from another edition of one of the Premier League's fiercest rivalry matches.

Amorim came in for a lot of criticism over his decision to play an ageing midfield of Casemiro and Eriksen against an energetic Newcastle United side in an eventual 2-0 defeat last time out. It could have been a lot worse in truth, and Amorim opts to completely change the two starting central midfielders here with Mainoo and Ugarte coming in. The other alteration sees Zirkzee, who was hooked for Mainoo in the first half against Newcastle, drop to the bench for the returning Fernandes, who captains the side after missing the defeat against the Magpies through suspension.

Slot makes just the one change to the team that started the 5-0 away thumping of West Ham last time out, with Konate replacing the injured Joe Gomez at centre-back. Alexander-Arnold, the subject of reported interest from Spanish giants Real Madrid, retains his place at right-back.

SUBS: Altay Bayindir, Joshua Zirkzee, Tyrell Malacia, Christian Eriksen, Leny Yoro, Alejandro Garnacho, Casemiro, Antony, Toby Collyer.

MANCHESTER UNITED (3-4-3): Andre Onana; Matthijs de Ligt, Harry Maguire, Lisandro Martinez; Noussair Mazraoui, Kobbie Mainoo, Manuel Ugarte, Diogo Dalot; Amad Diallo, Rasmus Hojlund, Bruno Fernandes.

SUBS: Wataru Endo, Darwin Nunez, Federico Chiesa, Harvey Elliott, Diogo Jota, Kostas Tsimikas, Caoimhin Kelleher, Jarell Quansah, Conor Bradley.

LIVERPOOL (4-2-3-1): Alisson; Trent Alexander-Arnold, Ibrahima Konate, Virgil van Dijk, Andy Robertson; Alexis Mac Allister, Ryan Gravenberch; Mohamed Salah, Curtis Jones, Cody Gakpo; Luis Diaz.

Any encouragement from Ruben Amorim's three-game unbeaten run to start life at Old Trafford has quickly dwindled, following it up with six defeats in eight in all competitions to leave them heading into this daunting away fixture 14th in the Premier League. Perhaps inconceivably, there are even concerns over whether United could yet find themselves in relegation trouble, and with their current form and just a six-point gap to the drop zone, Amorim and the Red Devils surely need to start putting more points on the board to avoid any late-season drama at the wrong end of the Premier League.

This game has beaten the weather after a flurry of snow, and the hosts will surely be chomping at the bit to play their out-form rivals. If it wasn't Liverpool's league to lose already, another slip-up from their closest title challengers Arsenal on Saturday away at Brighton has further cemented the status of Arne Slot's men as strong favourites for glory come May. They've rarely looked like stumbling this season, losing just once in the league, and another win here could extend their lead at the summit to a perhaps insurmountable eight points with a game in hand over second-placed Arsenal.