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US: AstraZeneca may have used outdated info in vaccine trial

U_S_ federal health officials say results from a U_S_ trial of AstraZeneca’s COVID-19 vaccine may have used “outdated information."

Via AP news wire
Tuesday 23 March 2021 03:21 EDT
Virus Outbreak Germany Vaccines
Virus Outbreak Germany Vaccines (AP)

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Results from a U.S. trial of AstraZeneca s COVID-19 vaccine may have used "outdated information," U.S. federal health officials said in a statement early Tuesday.

Late Monday, the Data and Safety Monitoring Board said in a statement that it was concerned that AstraZeneca may have provided an incomplete view of the efficacy data.

Late Monday, the Data and Safety Monitoring Board said in a statement that it was concerned that AstraZeneca the included outdated information from that trial may have provided an incomplete view of the efficacy data.

AstraZeneca reported Monday that its COVID-19 vaccine provided strong protection among adults of all ages in a long-anticipated U.S. study, a finding that could help rebuild public confidence in the shot around the world and move it a step closer to clearance in the U.S.

In the study of 30,000 people, the vaccine was 79% effective at preventing symptomatic cases of COVID-19 — including in older adults. There were no severe illnesses or hospitalizations among vaccinated volunteers, compared with five such cases in participants who received dummy shots — a small number, but consistent with findings from Britain and other countries that the vaccine protects against the worst of the disease.

AstraZeneca also said the study’s independent safety monitors found no serious side effects, including no increased risk of rare blood clots like those identified in Europe a scare that led numerous countries to briefly suspend vaccinations last week.

The company aims to file an application with the Food and Drug Administration in the coming weeks, and the government’s outside advisers will publicly debate the evidence before the agency makes a decision.

Authorization and guidelines for use of the vaccine in the United States will be determined by the Food and Drug Administration and Centers for Disease Control and Prevention after thorough review of the data by independent advisory committees.

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