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Surgeons transplant pig kidney into a patient in world first

The experimental transplant was done at the Boston hospital on Saturday

Ap Correspondent
Thursday 21 March 2024 10:47 EDT
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Pigs might one day help fill a shortage of donated organs
Pigs might one day help fill a shortage of donated organs (Copyright 2023 The Associated Press. All rights reserved.)

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Doctors have transplanted a pig kidney into a 62-year-old patient.

Massachusetts General Hospital said it’s the first time a genetically modified pig kidney has been transplanted into a living person. Previously, pig kidneys have been temporarily transplanted into brain-dead donors. Also, two men received heart transplants from pigs, although both died within months.

The experimental transplant was done at the Boston hospital on Saturday. The patient, Richard “Rick” Slayman of Weymouth, Massachusetts, is recovering well and is expected to be discharged soon, doctors said Thursday.

Slayman had a kidney transplant at the hospital in 2018, but had to go back on dialysis last year when it showed signs of failure. When dialysis complications arose, his doctors suggested a pig kidney transplant, he said in a statement released by the hospital.“I saw it not only as a way to help me, but a way to provide hope for the thousands of people who need a transplant to survive,” said Slayman.

The announcement marks the latest development in xenotransplantation, the term for efforts to try to heal human patients with cells, tissues, or organs from animals. For decades, it didn’t work — the human immune system immediately destroyed foreign animal tissue. More recent attempts have involved pigs that have been modified so their organs are more humanlike — increasing hope that they might one day help fill a shortage of donated organs.

Lawrence Faucette, who recieved a pig heart transplant
Lawrence Faucette, who recieved a pig heart transplant (AP)

More than 100,000 people are on the national waiting list for a transplant, most of them kidney patients, and thousands die every year before their turn comes.

Lawrence Faucette, who received a transplanted heart from a pig at the University of Maryland School of Medicine died in October last year.

Faucette, 58, was dying of heart failure before he received the transplant on 20 September and doctors said he wasn’t eligible for a human heart transplant due to other health conditions.

His case was the second in which University of Maryland doctors have tried to use a pig’s heart to save someone dying from heart disease.

The team performed the first transplant on David Bennett. He lived just two months with the pig’s heart; though it’s thought that a pig virus may have contributed to his death, the official cause has not been determined.

Before performing their second transplant – on Mr Faucette – the team reportedly implemented better virus testing on the pig heart.

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