Man dies from mystery Alaskapox – what you need to know about the virus

For nine years, Alaska health officials have been aware of an unusual virus causing rare, relatively mild illnesses in the Fairbanks area.

But a recent case in another part of the state — this one resulting in a man's death — has brought new attention to the so-called Alaskapox virus.

The man, who lived in the remote Kenai Peninsula, was hospitalized last November and died in late January, according to a bulletin last week from Alaska public health officials.

The man was undergoing cancer treatment and had a suppressed immune system because of the drugs, which may have contributed to the severity of his illness, the bulletin said. It described him as elderly but didn’t provide his age.

Alaskapox, also known as AKPV, is related to smallpox, cowpox and mpox, health officials said. Symptoms can include a rash, swollen lymph nodes and joint or muscle pain.

Only six other cases of the virus have been reported to Alaska health officials since the first one in 2015. All involved people were living in the Fairbanks area, more than 300 miles (483 kilometers) from the Kenai Peninsula, health officials said.

open image in gallery

It’s unclear how AKPV is transmitted but researchers say it may be zoonotic, meaning it can jump from animals to humans. The bulletin said that tests found evidence of current or previous infection in several species of small mammals in the Fairbanks area, including red-backed voles, and at least one domestic pet.

The man said he had cared for a stray cat at his home, the bulletin said.

The cat tested negative for the virus but it “regularly hunted small mammals and frequently scratched the patient,” the bulletin said.

open image in gallery

That opens the possibility that the cat had the virus on its claws when it scratched him. The bulletin said a “notable” scratch near the armpit area where the first symptom — a red lesion — was noted.

Health officials said there hasn’t been any documented cases of humans passing on the virus but they recommended people with skin lesions possibly caused by Alaskapox to cover the affected area with a bandage.”

Other suggestions are thoroughly washing hands, avoid sharing clothing that might have touched the lesions and to launder clothing and sheets separately from other household items.Health authorities also urged Alaskans to follow federal health precautions when around wildlife to avoid potential Alaskapox infections.

Here's what you need to know about the virus:

Alaskapox belongs to a family of brick-shaped viruses that can infect animals and humans. These bugs, known as orthopoxviruses, tend to cause lesions, or pox, on the skin. Each has its own characteristics, and some are considered more dangerous than others.

Smallpox is perhaps the most famous of the lot, but other family members include camelpox, cowpox, horsepox and mpox — formerly known as monkeypox.

Alaskapox was discovered in 2015 in a woman who lived near Fairbanks, Alaska. It mainly has been found in small mammals, including red-backed voles and shrews. But pets, such as dogs and cats, may also carry the virus, health officials say.

Seven people, all in Alaska, have been infected with it in the last nine years.

People with Alaskapox have developed one or more bumps or pustules on the skin, as well as joint or muscle pain and swollen lymph nodes.

Nearly all patients had mild illnesses that resolved on their own after a few weeks. But people with weakened immune systems can be in danger for more severe illness.

Officials believe Alaskapox spreads through contact with infected animals.

There has been no documented case of it spreading from one person to another. But other viruses in the same family can spread when one person comes in contact with another person’s lesions, so Alaska health officials are advising anyone with an Alaskapox lesion to cover it with a bandage.

Alaska health officials are aware of seven people infected with Alaskapox since the virus was discovered, but the latest case represents the first time someone is known to have died from it.

The elderly man, who lived in the Kenai Peninsula, was being treated for cancer and had a suppressed immune system because of the drugs. In September, he noticed a red sore under his right armpit and went to see doctors over the next two months because of fatigue and burning pain. He was hospitalized in November and died last month, according to a bulletin last week from Alaska public health officials.

The man lived in a remote forested area and did not travel. He had been repeatedly scratched by a stray cat that hunted small animals, and one of the scratches was in the area of the man's armpit, officials said.

Alaskapox is a rare illness that in most cases causes a relatively mild symptoms, health officials believe.

That said, wildlife can carry infections risks. Health officials say the best ways to keep pets and family members safe is to keep a safe distance and wash your hands after being outdoors. Also, not try to keep wildlife as pets.