") no-repeat center center;background-size:10px 16px;content:' '}@media(min-width:768px){.gBkjJh::before{display:none}}.hEDhTD{display:flex;justify-content:center;max-width:100%;margin:0 auto}.hEDhTD iframe{aspect-ratio:16/9;width:100%}@media(min-width:1000px){.iZwHvr .taboola{display:none}}.iZwHvr:has(#taboola-carousel-thumbnails){min-height:426px}.iZwHvr:has(#taboola-mid-article-thumbnails-crime){min-height:405px}@media(min-width:1000px){.iZwHvr:has(#taboola-carousel-thumbnails),.iZwHvr:has(#taboola-mid-article-thumbnails-crime){min-height:0}}.jImJId .tp-container-inner,.jImJId .sc-1suqprf-0{position:relative;box-shadow:0 -22px 16px 22px rgba(255,255,255,0.95)}.jImJId.closed{display:none}.buqclE{width:32px;color:#627aac}@media(min-width:768px){.buqclE.mobile-only{display:none}}.buqclE:hover{color:#9cabcb}.iVjrWB{width:32px;color:#4e4e4e}@media(min-width:768px){.iVjrWB.mobile-only{display:none}}.iVjrWB:hover{color:#919191}.icVQKT{width:32px;color:#25d366}@media(min-width:768px){.icVQKT.mobile-only{display:none}}.icVQKT:hover{color:#66e093}.gfyViz{width:32px;color:#ef4757}@media(min-width:768px){.gfyViz.mobile-only{display:none}}.gfyViz:hover{color:#f58992}.dJrOFo{display:flex;gap:12px}.eZumoJ{position:fixed;top:0;left:0;z-index:2147483644;background:rgba(0,0,0,0.5);cursor:pointer;opacity:0;transition:opacity 300ms ease-in-out}.eZumoJ.overlay-background--open{width:100vw;height:100vh;opacity:1}.dRVLpc{--trans:300ms ease-in-out;position:fixed;top:0;left:0;z-index:2147483645;width:100vw;height:100vh;opacity:0;pointer-events:none;transform:translateY(-24px);transform-origin:top center;transition:transform var(--trans),opacity var(--trans)}.dRVLpc.overlay--open{opacity:1;transform:translateY(0);transition-delay:150ms}.dRVLpc.overlay--open>:first-child{pointer-events:auto}.cWTSTp .sc-17yxc4y-0{display:none}.cWTSTp:hover .sc-17yxc4y-0,.cWTSTp.bookmark-button-saved .sc-17yxc4y-0{display:block}.cWTSTp:hover .sc-17yxc4y-1,.cWTSTp.bookmark-button-saved .sc-17yxc4y-1{display:none}.cWTSTp.bookmark-button-saved .sc-17yxc4y-0{display:block}.cWTSTp.bookmark-button-saved .sc-17yxc4y-1{display:none}.cWTSTp.bookmark-button-saved:hover .sc-17yxc4y-0{display:none}.cWTSTp.bookmark-button-saved:hover .sc-17yxc4y-1{display:block}.eoIBc{--margin-x:12px;--modal-width:calc(100% - (var(--margin-x) * 2));--modal-max-width:351px;--padding:60px 16px 42px;--line-height:1.25;display:flex;position:fixed;top:50%;left:50%;overflow:auto;width:var(--modal-width);max-width:var(--modal-max-width);max-height:100vh;box-sizing:border-box;flex-direction:column;align-items:center;justify-content:center;padding:var(--padding);background-color:#eaf2f2;box-shadow:0 1px 1px rgba(0,0,0,0.5);line-height:var(--line-height);transform:translate(-50%,-50%)}@media(min-width:768px){.eoIBc{--modal-width:600px;--modal-max-width:none;--padding:72px 80px 64px;--line-height:1.2}}@media(min-width:1000px){.eoIBc{--modal-width:635px}}.fNhASP{--close-button-margin:16px;position:absolute;top:var(--close-button-margin);right:var(--close-button-margin)}@media(min-width:768px){.fNhASP{--close-button-margin:24px}}.caBZHW{width:100%;max-width:437px;margin-bottom:20px}@media(min-width:768px){.caBZHW{margin-bottom:18px}}.dgWryu{position:absolute;overflow:hidden;width:.01em;height:.01em;padding:0;border:0;clip:rect(0,0,0,0);white-space:nowrap}.eUOcMf{width:100%;margin:0}.dEYNzg{margin:0 0 30px;font:bold 26px/1.15 'Indy Serif','Indy Serif Fallback',serif}@media(min-width:768px){.dEYNzg{font:bold 28px/1.15 'Indy Serif','Indy Serif Fallback',serif}}.itdeLI{display:block;width:100%;padding:0;margin:0 0 30px;font:normal 16px/1.44 'Indy Sans','Indy Sans Fallback',sans-serif}@media(min-width:768px){.itdeLI{font:normal 20px/1.44 'Indy Sans','Indy Sans Fallback',sans-serif}}.funPAy{display:block;margin-top:30px;color:#222;font:normal 16px/normal 'Indy Sans','Indy Sans Fallback',sans-serif}.bXVQbr{padding:0}.gzKeOP{display:inline-block;width:32px;height:32px;color:#70a5a7}.cJKiex{display:flex;flex-direction:row;justify-content:center;gap:12px}.hzDNyM{display:flex;position:relative;justify-content:center}@media(min-width:768px){.hzDNyM{justify-content:flex-end;padding-top:12px;margin:0}}.hzDNyM.amp-social-share svg{width:60%;height:60%;margin:20%;fill:#fff}.hzDNyM.amp-social-share [type='facebook'] svg,.hzDNyM.amp-social-share [title='bookmark'] svg{width:100%;height:100%;margin:0}.hzDNyM.amp-social-share amp-social-share{margin:0 6px;border-radius:50%;background:0;outline:0}.hzDNyM.amp-social-share amp-social-share:first-of-type{margin-left:0}.hzDNyM.amp-social-share amp-social-share:last-of-type{margin-right:0}@media(min-width:768px){.hzDNyM.amp-social-share .share-mobile-only{display:none}}.hzDNyM.amp-social-share .amp-social-share-bookmark svg{display:block;width:100%;height:100%;margin:0}.hzDNyM.amp-social-share .amp-social-share-bookmark:hover{opacity:.85}.hzDNyM.amp-social-share .amp-social-share-facebook{background:#627aac}.hzDNyM.amp-social-share .amp-social-share-facebook:hover{background:#9cabcb}.hzDNyM.amp-social-share .amp-social-share-twitter{--color:#4e4e4e;--color-alt:#919191;background:var(--color)}.hzDNyM.amp-social-share .amp-social-share-twitter:hover{background:var(--color-alt)}.hzDNyM.amp-social-share .amp-social-share-whatsapp{background:#25d366}.hzDNyM.amp-social-share .amp-social-share-whatsapp:hover{background:#66e093}.hzDNyM.amp-social-share .amp-social-share-whatsapp svg{width:70%;height:auto;margin:15%}.hzDNyM.amp-social-share .amp-social-share-email{background:#ef4757}.hzDNyM.amp-social-share .amp-social-share-email:hover{background:#f58992}.hzDNyM.amp-social-share .amp-social-share-email svg path{stroke:#fff}.kdvWjb{display:flex}.sticky .kdvWjb{flex-direction:column}.bfkmcy{overflow:hidden;height:23px;margin-bottom:8px;border-bottom:0;clear:both}@media(min-width:768px){.bfkmcy{height:25px}}.fczuIa{display:inline-block;flex-shrink:0;margin:0 12px 0 0;font:bold 14px/normal 'Indy Sans','Indy Sans Fallback',sans-serif}.fczuIa::after{content:':'}.IOUwh{display:inline-block;margin-right:12px;margin-bottom:4px;color:#222;font:normal 14px/1.29 'Indy Sans','Indy Sans Fallback',sans-serif;text-decoration:underline}.IOUwh::first-letter {text-transform:capitalize}@media(min-width:1000px){.subscribed .bwpCMN{margin-top:-184px}.article-feature:not(.article-feature-video) .subscribed .bwpCMN{margin-top:-407px}}.bwpCMN>p{margin:16px 0}.article-premium .bwpCMN>p{line-height:27px}.bwpCMN>h2{font-size:21px}.article-climate .bwpCMN>h2{color:#ec1a2e}.article-sgi .bwpCMN>h2{color:#ec1a2e}.bwpCMN>p:first-child{margin-top:0}.bwpCMN span:first-child~p:first-of-type{margin-top:0}.hQjaQn{display:flex;position:relative;max-width:100%;min-height:600px;justify-content:center;margin:0 auto;background-color:transparent;clear:both}@media(min-width:1000px){.hQjaQn{min-height:450px}}.teads .hQjaQn{display:block}.hQjaQn [data-mpu]{position:sticky;top:16px}@media(min-width:1000px){.jZcooN{display:none}}.jZcooN[data-mpu1]{min-height:600px}.jZcooN.pb-20{padding-bottom:20px}.hlPMMm{margin:0 0 24px;font:normal 16px/20px 'Indy Sans','Indy Sans Fallback',sans-serif}.euTVax{font:bold 16px/20px 'Indy Sans','Indy Sans Fallback',sans-serif}.jBfdop{overflow:hidden;width:100%;box-sizing:border-box;margin-bottom:16px}@media(min-width:768px){.jBfdop{max-width:634px}}@media(min-width:1250px){.jBfdop{max-width:622px}}.hKRbzg{width:100%;box-sizing:border-box;padding:8px 12px 12px;border-top:8px solid #ec1a2e;background-color:#fde8ea}@media(min-width:768px){.hKRbzg{padding-top:4px;padding-bottom:12px}}.cKIkhp{font:bold 22px/26px 'Indy Serif','Indy Serif Fallback',serif;margin:0 0 12px;text-align:center}@media(min-width:768px){.cKIkhp{font:bold 30px/34px 'Indy Serif','Indy Serif Fallback',serif;letter-spacing:-0.048px;margin-bottom:12px;text-align:left}}.feSJtK{display:block;margin-bottom:12px}@media(min-width:768px){.feSJtK{display:none}}.bErStG{display:flex;width:100%;box-sizing:border-box;align-items:center;justify-content:center;gap:4px;background-color:#fde8ea;color:#ec1a2e}@media(min-width:768px){.bErStG{width:auto;justify-content:flex-start}}.vaVnf{display:block;font:bold 14px/20px 'Indy Sans','Indy Sans Fallback',sans-serif;text-decoration-line:underline;margin-block:0;text-align:center}.jWuFRk{display:inline-flex;align-items:center;justify-content:center;gap:4px}.jWuFRk:hover .sc-hez36s-5,.jWuFRk:hover .sc-a5wy94-0{color:#ac2a2c}.hKrnEq{font:normal 16px/20px 'Indy Sans','Indy Sans Fallback',sans-serif}.dWUzhG{display:flex;width:100%;flex-direction:column}@media(min-width:768px){.dWUzhG{display:flow-root;gap:24px;transition:margin-bottom .3s ease-in-out}}.bDgIJb{display:flex;width:100%;flex-direction:column;align-items:center;justify-content:center}@media(min-width:768px){.bDgIJb{position:relative;z-index:1;width:212px;flex-shrink:0;justify-content:flex-start;margin-left:24px;float:right}}.EYumw{display:none;flex-direction:row;align-items:center;justify-content:center;gap:8px;margin-top:8px}@media(min-width:768px){.EYumw{display:flex;margin-top:12px}}.kCOwPr{display:flex;width:100%;align-items:center;justify-content:center;gap:8px;margin-top:8px;margin-bottom:12px}@media(min-width:768px){.kCOwPr{display:none}}.iGXncB{display:flex;overflow:hidden;height:0;flex-direction:column;gap:8px;opacity:0;transition:all .3s ease-in-out}@media(min-width:768px){.iGXncB{display:flex;position:relative;width:auto;height:40px;order:-1;opacity:1;transition-behavior:allow-discrete}.iGXncB::after{--fade-from:rgba(253,232,234,0);--fade-to:#fde8ea;position:absolute;bottom:0;left:0;z-index:1;width:100%;height:40px;background-image:linear-gradient(to bottom,var(--fade-from),var(--fade-to));content:'';opacity:1;transition:opacity 150ms ease-out}}@media(min-width:768px){.doTReP{order:-1}}.ggPDxB{display:none;padding-top:8px;margin-top:16px;border-top:1px solid #919191}@media(max-width:767px){.ggPDxB{display:flex}}.gibhIT{display:none}@media(min-width:768px){.gibhIT{display:flex;position:relative;align-items:flex-start;margin-top:12px}}.dxwzhm{display:flex;min-height:600px;justify-content:center}@media(min-width:1000px){.dxwzhm{min-height:450px}}.gHNATZ{min-height:600px}@media(min-width:1000px){.gHNATZ{min-height:450px}}.gHNATZ.mobile-only{display:block}@media(min-width:1000px){.gHNATZ.mobile-only{display:none}}.gHNATZ.desktop-only{display:none}@media(min-width:1000px){.gHNATZ.desktop-only{display:block;margin-bottom:16px}}.gHNATZ.desktop-only+p{margin-top:0}.gHNATZ .third-party-ad{position:sticky;top:16px}.bJycyU{width:100%;flex-grow:1}.bJycyU .amp-article-content[amp-access][amp-access-hide]{display:block;overflow:hidden;max-height:360px}.bJycyU .amp-article-content[amp-access][amp-access-hide] .social-share{display:none}.bJycyU .amp-article-content[amp-access][amp-access-hide].show-all-content{max-height:100%}@media(max-width:594px){.bJycyU .amp-article-content[amp-access][amp-access-hide]{max-height:530px}}.bJycyU .amp-newsletter-reg-gate{position:relative;left:-12px;width:calc(100% + 24px)}.bJycyU .social-share{width:100%;padding-top:10px;padding-bottom:20px}@media(min-width:768px){.bJycyU .social-share{justify-content:flex-start}}.bJycyU .social-share.sticky{display:none}@media(min-width:1000px){.bJycyU .social-share.sticky{display:flex;position:sticky;top:14px;width:34px;flex-direction:column;padding-top:0;margin-top:0;margin-left:-25%}.bJycyU .social-share.sticky amp-social-share,.bJycyU .social-share.sticky .sc-mgcah7-0{margin:0 0 16px}.article-feature-video .bJycyU .social-share.sticky{margin-top:0}.article-feature:not(.article-feature-video) .bJycyU .social-share.sticky{margin-top:35%}}.bJycyU.sponsored-article img,.bJycyU.sponsored-article video{width:100%;max-width:602px;height:auto}.bJycyU.sponsored-article iframe{max-width:602px;max-height:400px}.bJycyU .under-article-prompt-donations{padding-bottom:8px;margin-top:-3px}.bJycyU .big-letter{--color:#222;display:flex;position:relative;width:0;height:0;align-items:center;justify-content:center;padding:40px;margin-top:22px;margin-right:12px;border:1px solid var(--color);float:left;font:normal 52px/1 'Indy Serif','Indy Serif Fallback',serif;text-transform:uppercase}.bJycyU .big-letter:first-child{margin-top:6px}.bJycyU .big-letter::before{position:absolute;top:0;left:0;width:100%;height:100%;box-sizing:border-box;border:1px solid var(--color);border-radius:50%;content:''}.bJycyU #taboola-below-article-1{min-height:2350px}@media(min-width:768px){.bJycyU #taboola-below-article-1{min-height:3370px}}.bJycyU #taboola-below-article-1-split-num-1{min-height:130px}@media(min-width:768px){.bJycyU #taboola-below-article-1-split-num-1{min-height:415px}}.bJycyU .sc-fwko30-0+.sc-1xtsh2b-0{margin-top:-16px}@media(min-width:768px){.bJycyU{max-width:636px;margin:0}}@media(min-width:1000px){.bJycyU{max-width:624px;margin:0}.bJycyU.subscribed{max-width:636px}}@media(max-width:999px){.bJycyU{padding-right:0}.bJycyU .under-article-prompt-donations{margin-top:-18px}}.bJycyU .anchor-nav-header{scroll-margin-top:79px}.bJycyU .anchor-nav-header a{color:#222}.bJycyU .anchor-nav-header a:hover{color:#222}.kvSKnI{display:flex;flex-wrap:wrap;justify-content:flex-start;margin-bottom:8px;color:#646464;font:normal 16px/20px 'Indy Sans','Indy Sans Fallback',sans-serif}@media(min-width:768px){.kvSKnI{width:70%;align-items:center;justify-content:flex-start;margin-bottom:0;font:normal 16px/24px 'Indy Sans','Indy Sans Fallback',sans-serif}}@media(min-width:1000px){.kvSKnI{width:70%;margin-bottom:0}}.eXEVFg{display:flex;height:20px;margin:0 12px 8px 0}.article-voices .eXEVFg{height:auto}@media(min-width:425px){.article-voices .eXEVFg{height:20px}}.eXEVFg::before{display:inline-block;align-self:center;margin-top:1px;margin-right:12px;content:'\2022';transform:scale(1.5)}.eXEVFg:first-child::before{content:none}@media(min-width:768px){.eXEVFg{height:24px;margin-bottom:0}.eXEVFg::before{margin-top:2px}}.eXEVFg time{display:block}.eXEVFg time::first-letter {text-transform:capitalize}.eUdsoy{color:#fff}.jGlqRq{display:inline-block;margin:0 12px 8px 0;color:#ef4757;font:bold 16px/20px 'Indy Sans','Indy Sans Fallback',sans-serif;letter-spacing:-0.5px}.jGlqRq:hover,.jGlqRq:active{color:#f58992}@media(min-width:768px){.jGlqRq{margin-bottom:0}}.enHDwq{margin:0 4px 8px 0}.enHDwq::before{display:inline-block;margin-top:2px;margin-right:12px;color:#646464;content:'\2022';transform:scale(1.5)}.enHDwq:first-child::before{display:none}@media(min-width:768px){.enHDwq{margin-bottom:0}}.jmYqVV::before{color:#fff}.hfnwMY{display:flex;justify-content:flex-start;padding:0;margin:0 0 16px}@media(min-width:768px){.hfnwMY{display:flex;width:30%;align-items:center;justify-content:flex-end;margin:0}}@media(min-width:1000px){.hfnwMY{width:30%}}.hrDjjf{padding-top:0;border-top:0;border-bottom:0}@media(min-width:768px){.hrDjjf{display:flex;flex-flow:row wrap;padding-bottom:16px}.hrDjjf .sc-1qz44j0-0{order:1}.hrDjjf .sc-1qz44j0-10{order:2}}@media(min-width:1000px){.hrDjjf{flex-direction:row}}.dnLbAr{padding:16px 12px 12px;text-align:left;font:bold 14px/18px 'Indy Sans','Indy Sans Fallback',sans-serif}@media(min-width:768px){.dnLbAr{padding:16px 16px 12px}}.article-infact .dnLbAr{padding:16px 0}@media(min-width:1000px){.dnLbAr{padding:24px 0 19px}.article-feature .dnLbAr{max-width:968px;margin:0 auto}}.dnLbAr a{color:#fff}.dnLbAr a:hover{color:#f58992}.dnLbAr a:hover::after{color:#fff}.dnLbAr a::after{margin-right:4px;margin-left:4px;content:'>'}.dnLbAr a:last-child::after{display:none}.azcVx{margin:0 0 20px;letter-spacing:0}.VFZbw{margin:0;color:#646464;font:normal 16px/20px 'Indy Sans','Indy Sans Fallback',sans-serif}@media(min-width:768px){.VFZbw{font:normal 18px/22px 'Indy Sans','Indy Sans Fallback',sans-serif}}@media(min-width:1000px){.VFZbw{font:normal 20px/24px 'Indy Sans','Indy Sans Fallback',sans-serif}}.VFZbw p{font:inherit}.article-feature .VFZbw a{font-weight:bold}.hsJCLD{max-width:968px;margin:0 auto;background:#222}@media(min-width:1000px){.hsJCLD{padding:0 16px}.parallax .hsJCLD{max-width:1240px}}.bJjAgi{font:bold 32px/36px 'Indy Serif','Indy Serif Fallback',serif;letter-spacing:-0.0156em}@media(min-width:768px){.bJjAgi{font:bold 44px/48px 'Indy Serif','Indy Serif Fallback',serif;letter-spacing:-0.0113em}}@media(min-width:1000px){.bJjAgi{font:bold 54px/58px 'Indy Serif','Indy Serif Fallback',serif;letter-spacing:-0.0092em}}.hZFQIi{background:#222}.hZFQIi .sc-qvufca-1{max-width:968px;background:#222}.hZFQIi .sc-qvufca-0{margin:0}@media(max-width:999px){.hZFQIi .sc-qvufca-0{margin:0 12px 0}}.hZFQIi .sc-22qwnu-0,.hZFQIi .sc-22qwnu-0 a{color:#fff}.hZFQIi .sc-qvufca-2,.hZFQIi .sc-aeekvc-0{color:#fff}.hZFQIi .sc-qvufca-2{margin:0 0 20px}.hZFQIi .sc-aeekvc-0{margin-bottom:16px}@keyframes slidedown-video{from{transform:translateY(-100%)}to{transform:translateY(0)}}@keyframes slideup-video{from{transform:translateY(200%)}to{transform:translateY(0)}}.ghXxSp .video-top-container-inner{position:relative}.ghXxSp .video-popout-close{display:none}.ghXxSp .video-hero-wrapper-inner{display:block}.ghXxSp .video-hero-video{width:100%;margin:0;transition:height .2s}.ghXxSp .video-hero-wrapper.sticky-video{position:fixed;top:95px;width:400px;margin-left:-332px;transition:margin-left .3s,top .3s .1s}.ghXxSp .video-top-container.video.sticky:not(.closed) .video-hero-video{position:static;right:0;left:auto;width:100%}.ghXxSp .video-top-container.video.sticky:not(.closed) .video-hero-video.liveblog{margin-left:-12px}@media(min-width:768px){.ghXxSp .video-top-container.video.sticky:not(.closed) .video-hero-video{position:absolute;width:400px}}@media(min-width:1000px){.ghXxSp .video-top-container.video.sticky:not(.closed) .video-hero-video{top:94px;right:-56px}.ghXxSp .video-top-container.video.sticky:not(.closed) .video-hero-video.liveblog{right:-400px}}.ghXxSp .video-top-container.video.sticky:not(.closed) .video-hero-video .video-sticky-video{position:fixed;top:0;left:auto;z-index:9;width:100%;background-color:#fff;box-shadow:0 0 40px 10px rgba(0,0,0,0.5)}@media(min-width:768px){.ghXxSp .video-top-container.video.sticky:not(.closed) .video-hero-video .video-sticky-video{width:400px;animation:slidedown-video .4s}}@media(min-width:1000px){.ghXxSp .video-top-container.video.sticky:not(.closed) .video-hero-video .video-sticky-video{top:auto;bottom:0;animation:slideup-video .4s}}.ghXxSp .video-top-container.video.sticky:not(.closed) .video-popout-close{display:none;width:100%;box-sizing:border-box;align-items:center;justify-content:flex-end;padding:4px 8px 3px;color:#222;cursor:pointer;font-family:'Indy Sans','Indy Sans Fallback',sans-serif;font-size:14px;line-height:14px}@media(min-width:1000px){.ghXxSp .video-top-container.video.sticky:not(.closed) .video-popout-close{justify-content:flex-start}}.ghXxSp .video-top-container.video.sticky:not(.closed) .video-popout-close::after{display:flex;align-items:center;padding-left:4px;content:'\2715';font-size:12px}.ghXxSp .video-top-container.video.sticky:not(.closed) .video-popout-close.shown{display:flex}.JCJLP{max-width:100%;clear:both}.dyGKzS{--bleed:12px;display:flex;box-sizing:border-box;flex-direction:row;gap:32px;padding:16px var(--bleed);background-color:#fff}.article-liveblog .dyGKzS{background-color:#f7f7f7}@media(min-width:768px){.dyGKzS{--bleed:0;max-width:1000px;margin:0 auto}}@media(min-width:1000px){.dyGKzS{--bleed:16px;max-width:1000px;padding:var(--bleed)}}.gIldS{overflow:hidden;height:0;color:transparent}.kFPmfF{max-width:100%;margin:0 0 20px}.kFPmfF.sticky{position:sticky;top:16px}.iaRZct{min-height:600px}.iaRZct #mpu1{position:sticky;top:16px}.bFiDnI{min-height:250px}.jAzEot{max-width:100%}.eDScvc{margin:0 0 6px;color:#646464;font-family:'Indy Sans','Indy Sans Fallback',sans-serif;font-size:15px}.CmSgF{margin:0 0 12px}.lbFVDq{height:380px}.bsSHYO{width:100%;height:51px}.bjKtIv{margin-bottom:16px;border-bottom:1px solid #919191}.jLzsCV{margin-bottom:16px}.jLzsCV [role='listitem']{position:relative;margin-bottom:12px;border-bottom:1px solid #d3d3d3}.jLzsCV [role='listitem'] .sc-u4n1j-0{display:flex;position:absolute;bottom:16px;left:10px;width:32px;height:32px;align-items:center;justify-content:center;border-radius:50%;background-color:#ec1a2e}.jLzsCV [role='listitem'] .sc-u4n1j-0>svg{width:90%;fill:#fff;stroke:transparent}.jLzsCV [role='listitem']:first-child{display:block;padding-bottom:0;margin-bottom:12px}.jLzsCV [role='listitem']:first-child .sc-u4n1j-0{top:-15px;bottom:auto;left:12px;width:35px;height:35px}.jLzsCV [role='listitem']:first-child>*:first-child{display:block;width:100%;height:205px}.jLzsCV [role='listitem']:first-child>*:last-child{position:absolute;bottom:0;width:100%;padding:28px 12px 12px;background:linear-gradient(to top,#222 50%,rgba(34,34,34,0.9) 100%) no-repeat;color:#fff;font-size:17px;font-weight:bold}.jLzsCV [role='listitem']:last-child{margin-bottom:0;border-bottom:0 none}.kNZMQb{min-height:1924px}@media(max-width:767px){.kNZMQb{display:none}}.iFeFcz{width:308px}.iFeFcz.hidden{display:none}@media(max-width:999px){.iFeFcz{display:none}}.article-liveblog .fbWdwj{background-color:#f7f7f7}.eFgmkR{justify-content:center}.cvujVr{justify-content:center}
Lifestyle Health & Families Health News NHS to roll out new life-extending treatment for rare oesophagus cancer Around 3,000 people will become eligible for the new treatment in the UK
Subscribe to Independent Premium to bookmark this article Want to bookmark your favourite articles and stories to read or reference later? Start your Independent Premium subscription today.
Subscribe Already subscribed? Log in Worried about signs that could be cancer? Contact your GP
Your support helps us to tell the story From reproductive rights to climate change to Big Tech, The Independent is on the ground when the story is developing. Whether it's investigating the financials of Elon Musk's pro-Trump PAC or producing our latest documentary, 'The A Word', which shines a light on the American women fighting for reproductive rights, we know how important it is to parse out the facts from the messaging.
At such a critical moment in US history, we need reporters on the ground. Your donation allows us to keep sending journalists to speak to both sides of the story.
The Independent is trusted by Americans across the entire political spectrum. And unlike many other quality news outlets, we choose not to lock Americans out of our reporting and analysis with paywalls. We believe quality journalism should be available to everyone, paid for by those who can afford it.
Your support makes all the difference. Close Read more The NHS is to roll out a life-extending drug to patients with a rare form of throat and stomach cancer.
The National Institute for Health and Care Excellence (NICE) approved the use of Nivolumab – used to treat rare forms of gastroesophageal cancer - which will see around 3000 people eligible in the UK.
Nivolumab, also known as Opdivo, is a targeted immunotherapy designed to recognise and attach itself to a specific protein that can shut down the body’s immune system. The clinical evidence shows that, in blocking this action, 8 per cent of people achieve long-term remission compared to 4 per cent currently.
Gastroesophageal cancer includes tumours found anywhere in the oesophagus, sometimes called the gullet or food pipe, the stomach and where the oesophagus meets the stomach. At present, the most common treatments are surgery, radiotherapy, chemotherapy and immunotherapy drugs.
A clinical trial conducted by Bristol Myers Squibb – the company behind the drug – showed promising results amongst patients, studying 1581 cases of previously untreated advanced gastric cancer, gastroesophageal junction cancer and oesophageal adenocarcinoma.
Of these, 789 patients were given a combination of Opdivo and chemotherapy, while 792 were given chemotherapy alone. Overall, the survival rates proved stronger with the combination therapy: at one year, half of the patients trialled on Opdivo and chemotherapy went almost eight months without their cancer spreading, growing or getting worse compared to six months on those on chemotherapy alone.
Helen Knight, interim director of medicines evaluation at NICE, said: “The combination of nivolumab plus chemotherapy not only has the potential to slow the disease down and extend life for people with these forms of cancer, but there is some promise of long-term remission.
“We know there is a significant impact on the quality of life for people with these forms of advanced cancer and therefore I’m delighted that we have been able to recommend this innovative treatment for people with these rare forms of gastroesophageal cancer.
“We are determined to drive ground-breaking treatments such as this into the hands of health and care professionals.”
On NICE’s approval, NHS national cancer director, Professor Peter Johnson said: “Cancer of the oesophagus is one of the most difficult to diagnose and treat and this new life-extending drug, used with chemotherapy, will give hope to thousands of people with this illness, allowing them to spend more time with loved ones, enjoy a better quality of life and in some cases help them become cancer-free.
“It is yet another example of the NHS using its commercial capabilities to deliver cutting-edge drugs, combined with our work to catch cancers earlier than ever before, straight to patients who need them – giving them the best chance of surviving cancer.”
Thank you for registering Please refresh the page or navigate to another page on the site to be automatically logged in Please refresh your browser to be logged in
Join our commenting forum
Join thought-provoking conversations, follow other Independent readers and see their replies
Comments