Your support helps us to tell the story
From reproductive rights to climate change to Big Tech, The Independent is on the ground when the story is developing. Whether it's investigating the financials of Elon Musk's pro-Trump PAC or producing our latest documentary, 'The A Word', which shines a light on the American women fighting for reproductive rights, we know how important it is to parse out the facts from the messaging.
At such a critical moment in US history, we need reporters on the ground. Your donation allows us to keep sending journalists to speak to both sides of the story.
The Independent is trusted by Americans across the entire political spectrum. And unlike many other quality news outlets, we choose not to lock Americans out of our reporting and analysis with paywalls. We believe quality journalism should be available to everyone, paid for by those who can afford it.
Your support makes all the difference.A race is on to find the coronavirus vaccine: Oxford University and Imperial College London have been given a combined total of £84 million by the UK government to support their research.
On 20 July it was announced Britain had signed deals to secure 90 million doses of two potential coronavirus vaccines from the Pfizer Inc and BioNTech alliance and French group Valneva.
But the vaccine is still undergoing rigorous testing in the UK-based trials - including on human volunteers.
In May the first human trials began in England with 1,000 volunteers signing up to take part in the Oxford trial. Then on 16 June, Imperial College London began its human testing stage. In July Oxford University said the results were "promising".
But both groups are still looking for more recruits across England, Scotland and Wales.
Heres what you need to know.
Who is running the human vaccine trials?
Several countries are racing to find a vaccine for coronavirus,
In the UK, the first trials will be conducted by two universities – the University of Oxford and Imperial College London – as separate research projects.
If the trials are successful, the first vaccines could come into circulation by autumn this year.
What's the Oxford University vaccine?
The Oxford Vaccine Centre’s COVID-19 vaccine trial is run by the Jenner Institute and Oxford Vaccine Group, and is a collaborative project with several partners around the world.
Researches started working on possible vaccines on 10 January 2020 and now think they've found a suitable candidate.
The vaccine they are testing is a chimpanzee adenovirus vaccine vector (an inactive virus) currently named ChAdOx1, chosen because "it can generate a strong immune response from one dose and it is not a replicating virus, so it cannot cause an ongoing infection in the vaccinated individual".
These characteristics mean it's safe to be given to children, the elderly and those with pre-existing health conditions such as diabetes.
What's the Imperial College vaccine?
Researchers at Imperial College London have been working on a vaccine since early February.
Details of the vaccine hasn't been made public yet but is said to be a "self-amplifying RNA vaccine", essentially a protein that can replicate itself.
Researchers said: "When immune cells come across these proteins, they will react by creating antibodies to fight off the danger. But they also create a lasting memory of the threat for any future attack."
It's hoped that this vaccine will enable the body to learn to fight off the virus quicker in future.
Who can take part in the clinical trials and how can I get involved?
Oxford University started seeking healthy volunteers aged between 18 and 55 for their trials at the end of March.
They are now looking for more volunteers in the following areas: West Midlands, Thames Valley, north east of England, Southampton, Greater Glasgow and Clyde, London, Bristol, Sheffield, Merseyside, Hull, East Riding, south Wales, Cambridgeshire, Edinburgh and Nottinghamshire, Derbyshire, Lincolnshire and Leicestershire.
You can find out more about the trials and sign up online.
Imperial College has also joined the Oxford team and will be running the trials in London. Separately, they are also looking to start running trials of their version of the vaccine in June.
Join our commenting forum
Join thought-provoking conversations, follow other Independent readers and see their replies
Comments