13 best retinol creams and serums that are powerful and effective

Launched in the UK back in 2022, Naturium is a brand that offers effective formulas rooted in science at a good price point. This cream harnesses the power of retinaldehyde ­– which is more effective yet more gentle than retinol – to help target fine lines and uneven skin tone and texture. Our tester loved the lightweight formula of this cream, and we found that it absorbed quickly and didn’t cause any dryness or irritation, despite using it every night.

It’s one of the most affordable retinal formulas available, and we like that it’s also fragrance-free, making it suitable for pretty much all skin types. Combine that with the expensive-looking packaging and you’ve got a seriously impressive product that could easily cost a lot more than its £32 price point.

The Ordinary launched this serum earlier this year and it’s the most affordable and effective retinal formula we’ve found. A brand known for democratising skincare, this product doesn’t disappoint. Bolstered with 0.2 per cent retinaldehyde (it doesn’t soundl ike a lot, we know, but it’s enough to be extremely effective), it also contains oats for their soothing properties, which will also help reduce any sensitivity or dryness occurring. We love that it’s suitable for all skin types, and since only a pea-sized amount is needed a couple of times a week, this tube should last you a few months.

Another great choice for retinol newbies, our tester was impressed with the silky-feeling, lightweight texture of this product. Alongside pure retinol, it uses herbal extracts of myrtle which improves the overall efficacy of the serum, plus hero ingredient hyaluronic acid helps to lock in much-needed moisture for long-lasting hydration. Our tester noticed that her skin looked more radiant and smoother after just a couple of uses, and she didn’t get any dryness or irritation despite using it a bit more frequently than she would recommend.

Dermatica was the first brand to offer personalised prescription formulas, and it’s a firm favourite of our tester. Before purchasing, customers have to fill in an online consultation form and submit photos of their skin that a dermatologist will review. From there, skin concerns, alongside the results you’d ideally like, are considered and a custom, prescription-strength formula is made up and sent in the post.

While not all formulas will incorporate tretinoin (the most potent form of vitamin A), most will, and if you follow the instructions, results are pretty much guaranteed over the course of a few months. Our tester found that the cream serum did initially dry her skin out, but that subsided within a few weeks of use as skin acclimatised to it, and what followed was glowing skin and reduced breakouts.

Kate Somerville is a brand you can always rely on for creating potent, results-driven formulas, and this cream is no exception. While it may be pricey, it combines the power of both retinol and vitamin C and our tester loved the thick, comforting, velvety feel of this formula – it feels like the most luxe of the bunch.

Incredibly hydrating, thanks to the addition of hyaluronic acid, over time it will help to reduce the look of hyperpigmentation and will help to brighten the overall look of skin. It’s best to incorporate this cream into your routine slowly – to begin with, use it around twice a week and gradually increase use to prevent dryness.

One of our tester’s favourite brands, CeraVe’s take on retinol is as you’d expect: packed with skin-boosting ceramides, developed with sensitive skin in mind and helps maintain the delicate skin barrier. The formula is lightweight, absorbs quickly and contains encapsulated retinol alongside liquorice root extract and is designed to help reduce the look of any scarring left behind by acne, but it also helps brighten the skin.

Alongside being suitable for sensitive skin, it would also be a great entry point into retinol for anybody new to the ingredient or curious about it. Our tester also loved the inclusion of niacinamide – a hardworking, multi-tasking ingredient that not only works to soothe and strengthen skin but also helps to reduce oil production and the appearance of pores.

This moisturiser promises to calm blemishes overnight – something that our sceptical tester can vouch for. Alongside retinol, this clever moisturiser uses an ingredient called novoretin which helps to bolster its effects, plus it combines a blend of vitamin C and sulphur that work together to help visibly reduce spots and breakouts whilst working to smooth uneven texture.

On the surface, this moisturiser might sound like it has the potential to cause dryness, but our tester found the opposite. The texture of the cream itself is light and it sinks into the skin quickly. Considering its affordable price point, this moisturiser is an impressive multi-tasking hero perfect for anybody with acne- or breakout-prone skin.

A newly reformulated version of Nip+Fab’s retinol fix overnight cream, it’s now much better than the previous version. Instead of using a vitamin A derivative known as retinyl palmitate, it now features pure retinol, which is 20 per cent more potent, it uses clever time-release and encapsulation technology to ensure it’s able to effectively absorb into the skin and be as effective as possible. It also combines bakuchiol, a naturally occurring, plant-based retinol alternative proven to encourage skin cell turnover.

Our tester enjoyed using this light formula and loved that it also features ceramides to help smooth and hydrate skin. We also liked the fact there are multiple products within the retinol fix line meaning there is something to suit everybody across all skin types.

Another product that uses retinal, we’d recommend this particular bottle for seasoned retinol users. While our tester can’t vouch for its impressive – and transformative – stats, which say this moisturiser can smooth deep-set wrinkles in two weeks, and increase skin elasticity in four weeks, we can tell you that Murad is a brand we trust implicitly. This powerful but effective formula is a joy to use, and left our skin feeling soft and hydrated – and we didn’t notice any drying or sensitivity. It’s expensive, yes, but with a commitment to regular use, we think the results will speak for themselves.

This retinol serum comes from a revolutionary brand that, in our tester’s opinion, makes the use of upcycled ingredients exciting. You’ll find both retinol and retinal in this formula, which work in unison to promise quick, effective results, as well as upcycled raspberry and melon seed oils to soothe and hydrate the skin. We found it did take our skin a few uses to adjust to the formula, and we did sandwich it between moisturisers to help create a buffer, but there’s no denying that this cream packs a powerful punch in the best way possible. It’s one that we’d make sure you introduce slowly, and we did notice a slightly unpleasant smell at first but that quickly subsided.

Not just a great entry-level retinoid serum, this is also a great starting point if you’re new to Skin Rocks, Caroline Hirons’s brand. Using 0.2 per cent hydroxypinacolone retinoate – also known as HPR – it’ll help visibly reduce fine lines, dark spots and breakouts.

To help ensure skin remains nourished and hydrated, it’s also formulated with squalane and vitamin E, as well as bakuchiol and soybean extract which help boost the HPR’s effectiveness. A real hero product, we love how this made our skin feel, and the fact it’s also refillable is an extra added bonus.

You can always count on Medik8 to deliver an exceptional retinoid formula (or any skincare formula for that matter). Crystal retinal 10 is one of five different strengths available, and it’s one we would say is only best used by those who’ve been on their vitamin A journey for a while, who feel comfortable using it and who are looking for a step-up in terms of product strength and potency.

The unique formula means the serum remains stable (retinal is notoriously difficult to formulate with) while being incredibly effective. It’s boosted with hyaluronic acid, glycerin and vitamin E to help hydrate and nourish skin. As with other formulas, we would suggest introducing this one slowly into your routine, but over time we know it’ll help boost the skin’s radiance and improve its overall health.

SkinBetterScience is a brand that’s loved, used and recommended by almost every dermatologist and expert that our tester has spoken to – and for good reason. As a brand, it works with derms, plastic surgeons and other healthcare pros to deliver impressive, effective and best-in-class products.

This is one of its most talked about products from the brand, but before we continue, note that it is a prescription-strength formula so it does need to be purchased under the guidance of a professional (which can be done online). However, the formula itself is pretty impressive: it blends a retinoid with AHAs for visible skin improvement with minimal irritation. We would always suggest incorporating it into your routine slowly, but once your skin is fully acclimatised, the results will be impressive.